New and most accurate blood test for Alzheimer’s disease yet – will it help us predict the disease?

One major concern for brain health are the leading neurodegenerative diseases such as Alzheimer’s disease. New research has found a more accurate blood examing immune molecules to diagnose this disease.

…Kodadek says his team has applied the test to about 300 people, correctly diagnosing 98% of the people thought to have Alzheimer’s.

But does this blood test help us learn anything about the disease?

Wyss-Coray says it is still an open question as to whether or not people with Alzheimer’s produce antibodies that are specific to their condition. However, the small number of peptoids unique to those with the disease could point to a very specific immune response against an unknown disease molecule. “If true, that would most certainly change the current view of this disease.”

So this new blood test might lead to more accurate diagnosis of Alzheimer’s disease and possibly give us some insight into the mechanisms involved. Now, I wonder if they can find markers to help predict Alzheimer’s before we have the full disease so we are more likely to prevent this neurodegenerative disease. That is what we really require. And maybe there are hints of this from this statement.

Meanwhile, the test proved 95% accurate at distinguishing healthy people from those suspected to have Alzheimer’s, yet Kodadek doubts all 5% are true false positives. “I’m really pretty sure what we’re seeing is pre-symptomatic Alzheimer’s,” he says.

It is possilbe that the 5% false positives are ‘pre-sympptomatic’ and hence we have a better chance of treating to prevent or delay the onset of Alzheimer’s disease.

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